منابع مشابه
Raising HDL cholesterol in women
High-density lipoprotein cholesterol (HDL-C) concentration is essential in the determination of coronary heart disease (CHD) risk in women. This is especially true in the postmenopausal state, where lipid profiles and CHD risk mimic that of age-matched men. Thus, interventions designed to reduce CHD risk by raising HDL-C levels may have particular significance during the transition to menopause...
متن کاملReducing risk by raising HDL-cholesterol: the evidence
Low HDL-cholesterol is common among patients with cardiovascular disease. Well-designed epidemiological studies carried out over the previous three decades have defined the prognostic significance of low HDL-cholesterol. Indeed, a recent evaluation of patients undergoing coronary angiography showed that factors related to HDL-cholesterol, but not to LDL-cholesterol, were primarily responsible f...
متن کاملHigh-density lipoprotein metabolism and reverse cholesterol transport: strategies for raising HDL cholesterol
A key to effective treatment of cardiovascular disease is to understand the body's complex lipoprotein transport system. Reverse cholesterol transport (RCT) is the process of cholesterol movement from the extrahepatic tissues back to the liver. Lipoproteins containing apoA-I [highdensity lipoprotein (HDL)] are key mediators in RCT, whereas non-high-density lipoproteins (non-HDL, lipoproteins co...
متن کاملSecondary prevention by raising HDL cholesterol and reducing triglycerides in patients with coronary artery disease.
BACKGROUND Coronary heart disease patients with low high-density lipoprotein cholesterol (HDL-C) levels, high triglyceride levels, or both are at an increased risk of cardiovascular events, but the clinical impact of raising HDL-C or decreasing triglycerides remains to be confirmed. METHODS AND RESULTS In a double-blind trial, 3090 patients with a previous myocardial infarction or stable angi...
متن کاملRaising HDL cholesterol with low-dose nicotinic acid and bezafibrate: preliminary experience.
Nicotinic acid is an effective agent for elevating HDL cholesterol but is limited by side effects. In order to improve tolerance and lipid levels, we combined low-dose nicotinic acid with bezafibrate. We gave low-dose (mean 435 mg/day) nicotinic acid to 37 patients with low HDL cholesterol, bezafibrate (mean 476 mg/day) to 58 patients with elevated total cholesterol and both agents (mean nicoti...
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ژورنال
عنوان ژورنال: International Journal of Women's Health
سال: 2009
ISSN: 1179-1411
DOI: 10.2147/ijwh.s5110